Los coronavirus son patógenos con impacto en la salud humana y animal. En su mayoría causan enfermedades entéricas o respiratorias, que pueden ser potencialmente graves o mortales.La tasa de mortalidad al 20 de febrero se encuentra en 3,8 %.

La ciudad de Wuhan en China es el centro de atención mundial debido a un brote de enfermedad respiratoria febril a causa de un coronavirus 2019-nCoV. La secuencia genética del 2019-nCoV se puso a disposición de la OMS el 12 de enero de 2020 y esto ha facilitado a los laboratorios de diferentes países a producir pruebas de diagnóstico de PCR específicas para detectar la nueva infección ( OMS, 2020 ). El 2019-nCoV es un β CoV del grupo 2B con al menos un 70% de similitud en la secuencia genética con el SARS-CoV y ha sido nombrado 2019-nCoV por la OMS.

Monitoreo del Coronavirus en tiempo real

Se muestra en el mapa las estadísticas sobre el número de muertes y casos confirmados de coronavirus, 2019-nCoV(Covid -19)

(mapa elaborado por Johns Hopkins University)

Pulsar aquí si no puede visualizar o revisar en Versión móvil.

Despliegue los items para mayor información respecto a los temas de su interés. 

[expand title=”Vigilancia y Documentos Técnicos” swaptitle=”Vigilancia y Documentos Técnicos”]

Vigilancia y Documentos Técnicos OMS Coronavirus (2019-nCoV)

 

 

International Clinical Trials Registry Platform

 

 

Vigilancia OPS Coronavirus(2019-nCoV)

 

 

CDC 2019 Novel Coronavirus, Wuhan, China

Novel Coronavirus Reports

 

Documentos técnicos para profesionales

 

 

Casos globales de Coronavirus 2019-nCoV Johns Hopkins

 

 

Protocolo para la atención de personas sospechosas o infección confirmada por coronavirus (2019-nCoN)

 

 

Documento técnico atención y manejo clínico de casos de Covid-19. Escenario de transmisión focalizada.

 

 

European Centre for Disease Prevention and Control

 

 

 

[/expand]

[expand title=”Centros de Información de editoras científicas” swaptitle=”Centros de Información”]

Novel Coronavirus Information Center. Elsevier’s free health and medical research on novel coronavirus (COVID-19)

 

 

Coronavirus | Springer Nature

 

 

[/expand]
[expand title=”Generalidades – Artículos en inglés y otros idiomas” swaptitle=”Generalidades”]

Información actualizada al 14 de setiembre de 2020

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J Neuroimmune Pharmacol. 2020 jul 21. DOI: 10.1007/s11481-020-09944-5
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Eur J Pharmacol. 2020 jul 16. DOI: 10.1016/j.ejphar.2020.173375
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Allergy. 2020 jun 14. DOI: 10.1111/all.14449
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Review |  International Journal of Environmental Research and Public Health. 2020 april 14. 
DOI: https://doi.org/10.3390/ijerph17082690

 

A new pandemic out of China: the Wuhan 2019-nCoV coronavirus syndrome

 

 

Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19)

 

 

Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19)

 

 

Novel Coronavirus COVID-19. Current Evidence and Evolving Strategies

 

 

Coronaviruses and SARS-CoV-2. A Brief Overview

 

 

Coronavirus SARS-CoV-2: filtering out fact from fiction in the infodemic Q&A with virologist Prof. Urs Grebe

 

 

SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far

 

 

COVID-19: what has been learned and to be learned about the novel coronavirus disease

 

 

COVID-19: a novel zoonotic disease caused by a coronavirus from China: what we know and what we don’t

 

 

Novel Coronavirus Infection (COVID-19) in Humans: A Scoping Review and Meta-Analysis

 

 

SARS-CoV-2: What do we know so far?

 

 

COVID-19, a worldwide public health emergency

Español

 

A review of the 2019 Novel Coronavirus (COVID-19) based on current evidence 

 

 

SARS-CoV-2 and COVID-19: The Most Important Research Questions

 

 

COVID-19: Knowns, Unknowns, and Questions

 

 

The Outbreak of COVID-19: An Overview

 

 

Asymptomatic Carrier State, Acute Respiratory Disease, and Pneumonia Due to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Facts and Myths

 

 

A Review of Coronavirus Disease-2019 (COVID-19)

 

 

Novel coronavirus 2019-nCoV: prevalence, biological and clinical characteristics comparison with SARS-CoV and MERS-CoV

 

 

Understanding of COVID-19 Based on Current Evidence

 

 

The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status

 

 

Coronavirus Disease 2019 (COVID‐19): What we know?

 

 

COVID-19: the medium is the message

 

 

World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)

 

 

COVID-19 in Singapore—Current Experience. Critical Global Issues That Require Attention and Action

 

 

The coronavirus 2019-nCoV epidemic: Is hindsight 20/20?

 

 

Taking the right measures to control COVID-19

 

 

An outbreak of COVID‐19 caused by a new coronavirus: what we know so far

 

 

From the frontlines of COVID-19 – How prepared are we as obstetricians: a commentary

 

 

Q&A: The novel coronavirus outbreak causing COVID-19

 

 

The COVID-19 outbreak and implications for the Tokyo 2020 Summer Olympic Games

 

 

Recent insights into 2019-nCoV: a brief but comprehensive review

 

 

The epidemic of 2019-novel-coronavirus (2019-nCoV) pneumonia and insights for emerging infectious diseases in the future

 

 

Coronavirus Disease 2019 (COVID-19): A Perspective from China.

 

 

Online mental health services in China during the COVID-19 outbreak

 

 

Mental health care for medical staff in China during the COVID-19 outbreak

 

 

Initiation of a new infection control system for the COVID-19 outbreak

 

 

2019 Novel coronavirus: where we are and what we know

 

 

Wuhan coronavirus (2019-nCoV): The need to maintain regular physical activity while taking precautions

 

 

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

 

 

Preparation for Possible Sustained Transmission of 2019 Novel Coronavirus. Lessons From Previous Epidemics

 

 

A qualitative study of zoonotic risk factors among rural communities in southern China

 

 

Visión general del nuevo coronavirus (2019-nCoV)

 

 

Novel Wuhan (2019-nCoV) Coronavirus

 

 

SARS-CoV, MERS-CoV and now the 2019-novel CoV: Have we investigated enoughabout coronaviruses? – A bibliometric analysis

 

 

Offline: 2019-nCoV outbreak—early lessons

 

 

Emerging understandings of 2019-nCoV

 

 

IDM editorial statement on the 2019-nCoV

 

 

The Continuing 2019-nCoV Epidemic Threat of Novel Coronaviruses to Global Health – The Latest 2019 Novel Coronavirus Outbreak in Wuhan, China

 

 

[/expand]

Epidemiología – Artículos en inglés y otros idiomas

Etiopatogenia y Genética – Artículos en inglés

Diagnóstico y Tratamiento – Artículos en inglés y otros idiomas

[expand title=”Artículos Preprint” swaptitle=””Artículos Preprint”]

Información actualizada al 28 de mayo de 2020

Generalidades

AUTOR: Homolak, J.; Kodvanj, I.; Virag, D.
Preprints 2020, 2020030443  doi: 10.20944/preprints202003.0443.v1.

Epidemiología

AUTOR: Cuihua Shen, Anfan Chen, Chen Luo…[et all.].
J Med Internet Res. 2020 may 25. DOI: 10.2196/19421
AUTOR: Monia Makhoul, Houssein H Ayoub, Hiam Chemaitelly, Shaheen Seedat, Ghina R Mumtaz, Sarah Al-Omari, Laith J Abu-Raddad
medRxiv 2020.04.19.20070805; doi: https://doi.org/10.1101/2020.04.19.20070805

 

COVID-19 pandemic: Impact of lockdown, contact and non-contact transmissions on infection dynamics

 

 

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Contamination in Air and Environment in Temporary COVID-19 ICU Wards

 

 

Efficient sample pooling strategies for COVID-19 data gathering

 

 

The effect of control measures on COVID-19 transmission in Italy: Comparison with Guangdong province in China

 

 

Evidence that higher temperatures are associated with lower incidence of COVID-19 in pandemic state, cumulative cases reported up to March 27, 2020

 

 

Predicting clinical needs derived from the COVID-19 pandemic: the case of Spain

 

 

Increased circulating microparticles and inflammatory factors aggravate coronavirus disease 2019 (COVID-19)   

 

 

Transmission Dynamics and Control Methodology of COVID-19: a Modeling Study

 

 

Spatial Statistics and Influencing Factors of the Epidemic of Novel Coronavirus Pneumonia 2019 in Hubei Province, China

 

 

Infodemiological study on COVID-19 epidemic and COVID-19 infodemic

 

 

Outbreak Measures Taken by Medical Schools During the Coronavirus Pandemic in London, United Kingdom: A Qualitative Study

 

 

The Impact of Isolation on the Transmission of COVID-19 and Estimation of Potential Second Epidemic in China

 

 

Developing a Low-Cost and Accessible COVID-19 Vaccine for Global Health

 

 

Susceptibility of ferrets, cats, dogs, and different domestic animals to SARS-coronavirus-2

 

 

International Tourism and COVID-19: Recovery Strategies for Tourism Organisations 

 

 

What is required to prevent a second major outbreak of the novel coronavirus SARS-CoV-2 upon lifting the metropolitan-wide quarantine of Wuhan city, China 

 

 

Evaluating the effectiveness of social distancing interventions against COVID-19

 

 

Dynamic Modeling to Identify Mitigation Strategies for Covid-19 Pandemic    

 

 

Ecological and Health Infrastructure Factors Affecting the Transmission and Mortality of COVID-19   

 

 

Flattening the curve fails unless done very early: results from a simulation of ICU capacity in Chicago

 

 

Modeling Survival Time to Recovery from COVID-19: A Case Study on Singapore   

 

 

New dynamical behaviour of the coronavirus (COVID-19) infection system with nonlocal operator from reservoirs to people

 

 

Novel Coronavirus (COVID-19) in India 

 

 

A systematic review investigating the effectiveness of face mask use in limiting the spread of COVID-19 among medically not diagnosed individuals: shedding light on current recommendations provided to individuals not medically diagnosed with COVID-19 

 

Preparation for the quarantine of the cruise ship for SARS-CoV-2 (COVID-19) infection: The Diamond Princess in Japan

 

 

Etiopatogenia y genética

COVID-19: Attacks the 1-Beta Chain of Hemoglobin and Captures the Porphyrin to Inhibit Human Heme Metabolism

 

 

The Disruption of SARS-CoV-2 RBD/ACE-2 Complex by Ubrogepant Is Mediated by Interface Hydration

 

 

Inhibition of Viral Macrodomain of COVID-19 and Human TRPM2 by losartan

 

 

 Lectin-like Intestinal Defensin Inhibits 2019-nCoV Spike binding to ACE2

 

 

Computational Design of Peptides to Block Binding of the SARS-CoV-2 Spike Protein to Human ACE2

 

 

Cigarette smoke triggers the expansion of a subpopulation of respiratory epithelial cells that express the SARS-CoV-2 receptor ACE2

 

 

Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

 

 

Atlas of ACE2 gene expression in mammals reveals novel insights in transmission of SARS-Cov-2

 

 

Structural analysis of SARS-CoV-2 and prediction of the human interactome

 

 

 Re-insights into origin and adaptation of SARS-CoV-2

 

 

Predicting Broad-Spectrum Antiviral Drugs against RNA Viruses Using Transcriptional Responses to Exogenous RNA

 

 

COVID-19: A Drug Repurposing and Biomarker Identification by Using Comprehensive Gene-Disease Associations through Protein-Protein Interaction Network Analysis

 

Diagnóstico y Tratamiento

Therapeutic Preferences for Coronavirus 2(SARS-CoV-2) Patients

 

 

Dynamic changes in clinical and CT characteristics of COVID-19 cases with different exposure histories: a retrospective study

 

 

Blood glucose levels in elderly subjects with type 2 diabetes during COVID-19 outbreak: a retrospective study in a single center

 

 

Correlation analysis between disease severity and clinical and biochemical characteristics of 143 cases of COVID-19 in Wuhan, China: a descriptive study

 

 

Quantified CT Evaluation in coronavirus disease (COVID-19): A study of 30 Patients in Chongqing, China     

 

 

Optimal timing for social distancing during an epidemic

 

 

Three Unsuspected CT Diagnoses of COVID-19

 

 

Evaluation of variation in D-dimer levels among COVID-19 and bacterial pneumonia: a retrospective analysis

 

 

Drug repurposing against MERS CoV and SARS-COV-2 PLpro in silico

 

 

CT Imaging Changes of Corona Virus Disease 2019 (COVID-19):A multi-center study in Southwest China

 

 

The miRNA COMPLEXES AGAINST CORONAVIRUSES COVID-19, SARS-CoV, and MERS-CoV

 

 

Revealing Anti-viral Potential of Bio-active Therapeutics Targeting SARS-CoV2- polymerase (RdRp) in Combating COVID-19: Molecular Investigation on Indian Traditional Medicines

 

Eucalyptol (1,8 cineole) from Eucalyptus Essential Oil a Potential Inhibitor of COVID 19 Corona Virus Infection by Molecular Docking Studies

 

 

A one-enzyme RT-qPCR assay for SARS-CoV-2, and procedures for reagent production

 

 

Azithromycin and ciprofloxacin have a chloroquine-like effect on respiratory epithelial cells

 

 

Rapid Prototyping of Reusable 3D-Printed N95 Equivalent Respirators at the George Washington University    

 

 

Evaluation the auxiliary diagnosis value of antibodies assays for detection of novel coronavirus (SARS-Cov-2) causing an outbreak of pneumonia (COVID-19)

 

 

Role of Chloroquine and Hydroxychloroquine in the Treatment of COVID-19 Infection- A Systematic Literature Review

 

 

Deep Learning-Based Recognizing COVID-19 and other Common Infectious Diseases of the Lung by Chest CT Scan Images

 

 

Traditional Chinese herbal medicine for treating novel coronavirus (COVID-19) pneumonia: protocol for a systematic review and meta-analysis

 

 

Serum Amyloid A Protein as a Potential Biomarker Useful in Monitoring the Course of COVID-19 : A Retrospectively Studied 

 

 

Epidemiological and clinical characteristics of COVID-19 patients in Nanjing

 

 

Early CT manifestations and short-term evolution of coronavirus disease-2019

 

 

A Method of Estimating Time-to-Recovery for a Disease Caused by a Contagious Pathogen like SARS-CoV-2 using a Time Series of Aggregated Case Reports

 

 

Clinical retrospective analysis of 70 discharged patients with the Coronavirus disease 2019 (COVID-19) in Hangzhou, Zhejiang Province

 

 

Rapid Detection of 2019 Novel Coronavirus SARS-CoV-2 Using a CRISPR-based DETECTR Lateral Flow Assay 

 

 

Clinical and radiological features of patients with 2019 novel coronavirus (SARS-CoV-2) in Haikou, China    

 

 

Radiographic severity index in COVID-19 pneumonia: relationship to age and sex in 783 Italian patients      

 

 

Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2) infection during late pregnancy: A Report of 18 patients from Wuhan, China

 

 

Identification of Dietary Molecules as Therapeutic Agents to Combat COVID-19 Using Molecular Docking Studies     

 

      

Different clinical presentations of two renal transplant recipients with Coronavirus Disease 2019: a case report  

 

 

Caspofungin and LTX-315 inhibit SARS-CoV-2 replication by targeting the nsp12 polymerase

 

 

In silico elucidation revealed SARS CoV and MERS CoV Drug Compounds could be Potential Therapeutic Candidates against Post Fusion Core (S2) Protein of Novel Coronavirus (2019-nCov)

 

High resolution computed tomography for the diagnosis of 2019 novel coronavirus (2019-nCoV) pneumonia: a study from multiple medical centers in western China

 

 

Why re-purposing HIV drugs Lopinavir/ritonavir to inhibit the SARS-Cov2 protease probably wont work – but re-purposing Ribavirin might since it  has a very similar binding site within the RNA-polymerase

 

Patients of COVID-19 May Benefit From Sustained Lopinavir-Combined Regimen and the Increase of Eosinophil May Predict the Outcome of COVID-19 Progression

 

 

COVID-19 in Children: Initial Characterization of the Pediatric disease

 

 

[/expand]

[expand title=”Recursos de Formación” swaptitle=”Recursos de Formación”]

Recursos de Formación

Emerging respiratory viruses, including nCoV: methods for detection, prevention, response and control

Developed by the World Health Organization, this course provides a general introduction to nCoV and emerging respiratory viruses and is intended for public health professionals, incident managers and personnel working for the United Nations, international organizations and NGOs.

SCCM Critical Care for Non-ICU Clinicians-COVID-19 Resources

The Society of Critical Care Medicine (SCCM) is providing free education to inform, prepare, and equip ICU and other healthcare clinicians during the coronavirus disease 2019 (COVID-19) pandemic. Educational materials will be updated on this site as they become available.

[/expand]

Contacto

Unidad Funcional de Promoción de la Gestión del Conocimiento
Telf. 7480000 anexo 2194
oeidoc@ins.gob.pe,  pgcins@gmail.com

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